Amobi Okoye is a former NFL defensive tackle who was diagnosed with anti-NMDA receptor encephalitis in 2013 at just 27 years old. Credit: Amobi Okoye

Amobi Okoye didnโ€™t grow up dreaming of the NFL. 

In fact, when he moved to the U.S. from Nigeria at age 12, he didnโ€™t even know what football was. 

โ€œI saw it maybe once or twice on TV and just thought, โ€˜Why are they hitting each other like that?โ€™โ€ he said.

But just a few years later, at age 19, Okoye became the youngest first-round draft pick in NFL history. Born in Anambra State, Nigeria and part of the Igbo ethnic group, Okoye arrived in Huntsville, Alabama, with his family in the late ’90s. 

Like many immigrant kids, he was adjusting to a new world. What set him apart wasnโ€™t just his intelligence; it was the speed with which he adapted. After just two weeks in middle school, he tested into ninth grade. 

But at that point, he had never played American football. That changed in high school thanks to a coach who spotted Okoye and suggested he try out. 

โ€œHe looked at me and said, โ€˜You should come out for football,โ€™โ€ Okoye recalled. 

A close friend, already on the team, encouraged the challenge. Okoye was in.

The Houston Texans drafted Amobi in the first round of the 2007 NFL draft. He is the youngest player to be drafted in the first round of the NFL draft at only 19 years old. Credit: Amobi Okoye

He had no idea how the game actually worked. 

โ€œThey told me to go play Madden to learn,โ€ he laughed. โ€œI was literally learning football from a video game.โ€

Okoye was trying to get in shape. He had joined JROTC, but didnโ€™t enjoy it. He enrolled in track and field and leaned on his soccer background to build stamina. Slowly, the athlete in him took over. 

โ€œI was getting a little obese eating American food,โ€ he said. โ€œSo I got serious.โ€

Okoye earned All-State honors by his senior year as a defensive and offensive tackle and had offers from top-tier colleges.

In his household, education was non-negotiable. 

โ€œIt was always, โ€˜education, education, education,โ€™โ€ he said. โ€œMy dad was excited when Harvard showed interest. But I was thinking about football. Louisville had the better program. Thatโ€™s where I went.โ€

He enrolled as a 15-year-old biology major, later switched to psychology and graduated in just three and a half years. At 16, he became the youngest player in NCAA Division I football. He entered the NFL Draft when he was 19.

His mother, Edna Okoye, remembers being caught completely off guard by her sonโ€™s interest in the sport.

โ€œNo! We didnโ€™t know anything about football. We only saw it once in a movie, and we didnโ€™t even understand what it was,โ€ she told the Defender. โ€œHe always said he wanted to be a doctor, even a pastor at one point. Football? That wasnโ€™t in the picture.โ€

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Okoye was selected 10th overall by the Houston Texans in the 2007 NFL Draft. But even with his rising profile, he didnโ€™t expect to land in Houston.

The moment was surreal for the Okoye family. 

โ€œI didnโ€™t even understand what the draft was,โ€ Edna admitted. โ€œPeople kept asking me questions and calling me, and I didnโ€™t know why. When I realized he got picked, we were happy and thanked God.โ€

โ€œThe Texans interviewed me at the combine, but they didnโ€™t show any extra interest,โ€ he recalled. โ€œSo when they called my name, it was shocking, but perfect.โ€

The choice hit especially close to home for his family. 

โ€œMy dad was the most hyped. When he left Nigeria to come to the U.S., Houston was on the top of his list,โ€ Okoye said. โ€œSo when I got drafted, he said, โ€˜Iโ€™m going back home.โ€™โ€

Houston embraced him. The diversity, energy and connection to African culture all clicked. 

โ€œThis city has a huge African population,โ€ he said. โ€œThe love for their hometown teams is real. Win, lose, or draw, fans here still show up.โ€  

Okoye settled in Katy and has stayed in the Houston area ever since.

The medical battle that changed everything

In 2013, at just 27, Okoye suffered a seizure in his office, his first warning sign of a rare and devastating condition called anti-NMDA receptor encephalitis, a form of autoimmune encephalitis that causes the body to attack its brain receptors.

Within five months, certain parts of his memory disappeared. 

โ€œI thought it was still March 15th, the day of my first seizure, when I woke up in August,โ€ Okoye said. โ€œI couldnโ€™t remember anything.โ€

Doctors placed him in a medically induced coma to control recurring seizures. He became the first NFL player diagnosed with the condition and one of the first adult male athletes to publicly survive it. The illness gained more awareness through the book and Netflix film Brain on Fire, which chronicles a similar case.

โ€œI lost all sense of time,โ€ he said. โ€œItโ€™s a very rare illness. They diagnosed it with a spinal tap and finally got me the treatment I needed.โ€

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Recovery was slow, brutal and uncertain. He stayed in intensive care for 12 weeks, lost weight and mobility in his body, but Okoye was determined to return to football. So, he retrained his body one step at a time. 

After stints with the Chicago Bears and the Tampa Bay Buccaneers, he signed with the Dallas Cowboys in 2014. Though he was cleared to play, his body hadnโ€™t fully recovered. 

โ€œI gave everything to make it back,โ€ he said. โ€œBut it wasnโ€™t going to happen.โ€

His NFL career was over at the age of 29.

Amobi Okoye Foundation community activities. Credit: Amobi Okoye

Life after football

There was no roadmap for what came next. 

โ€œI had to figure it out,โ€ Okoye said. โ€œBut I already had other things going, such as my foundation, a marketing company and farming in Nigeria. I just kept building from there.โ€

โ€œFrom the time he got drafted, he was thinking about what he could do for youth,โ€ Edna said. โ€œHeโ€™s always been selfless like that. Heโ€™s doing it here in Houston, and heโ€™s doing it in Nigeria too. I just pray God continues to give him the strength to keep going.โ€

The Amobi Okoye Foundation became his focus. Its programs serve youth across Houston and beyond, offering football camps, book readings, motivational movie nights, school visits and food distribution events. He collaborates regularly with the Texansโ€™ community outreach team.

โ€œYoung athletes and their parents often think talent is enough. But itโ€™s more than that,โ€ Okoye said. โ€œYouโ€™ve got to go all-in. Do every part of it. School, discipline, nutrition, mindset. And even then, prepare for life after the game.โ€

Okoye no longer wears a jersey, but his work is far from over. 

โ€œThis city has given me so much. Thatโ€™s why Iโ€™m here. Thatโ€™s why I give back.โ€

I cover Houston's education system as it relates to the Black community for the Defender as a Report for America corps member. I'm a multimedia journalist and have reported on social, cultural, lifestyle,...